Atelier Sophie 2: The Alchemist of the Mysterious Dream is the 23rd main entry in the Atelier series. It's the fourth entry in the Mysterious sub-series of games.
- "Atelier Sophie 2: The Alchemist of the Mysterious Dream continues the story of Sophie and Plachta’s many adventures. After leaving Sophie’s hometown of Kirchen Bell, the pair discovers a huge tree identical to one that Plachta had seen in a dream, and as they get closer, a mysterious vortex pulls them inside. Sophie awakens alone in a curious new world called Erde Wiege, and it’s not long before she hears about an alchemist named Plachta that lives on the outskirts of town. Shockingly, when Sophie arrives at the atelier, she meets a young alchemy enthusiast named Plachta, and even though the alchemist shares the same name as her friend, she doesn’t recognize Sophie. What other surprises await Sophie on this journey? As the adventure continues, Sophie meets aspiring alchemist, Ramizel Erlenmeyer, who willingly agrees to help her in her time of need."
- — Official story description
The game features a turn-based combat system with 6 characters participating (3 in the front and 3 in the back). The system is described as a "multi-linked turn-based" system. Battles takes place on the field, without loading screens.