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Lilie is the main protagonist of Atelier Lilie: The Alchemist of Salburg 3. She also appears in Nelke & the Legendary Alchemists: Ateliers of the New World.
Lilie is a young and aspiring alchemist from the city of Kenntnis on the Isle of El Bador.
She got caught up in the alchemy trend sweeping Kenntnis, but her family lacked the resources to let her attend proper alchemy education. This did however not stop Lilie, who studied on her own instead. Her efforts and talent were eventually recognized by the Kenntnis Academy, and the senate saw enough potential in her to send her alongside Drnie to open an academy in the city of Salburg.
Lilie's skills as an alchemist are actually not that impressive at first, but she has the ability to catch on to new things quickly, be it alchemy or social cues. However, her easily excitable personality also often lead to her messing up. 
With the assistance of Hermina and Ingrid, Lilie must create items using alchemy to gain support from the people of Salburg. The King and the people of the country need to support the building of the academy financially, so Lilie must prove the worth of alchemy and help gather the funds necessary to build the academy.
Like the previous protagonists, Lilie must fight monsters, gather materials, synthesize items and do requests to gain a favorable reputation.
Lilie is the main protagonist of Atelier Lilie: The Alchemist of Salburg 3 and the character the player will take the role of. Lilie's main task is to gather funds for the academy, mainly by her alchemy skills. Occasionally, there will also be dialogue options for what Lilie should say.
Hermina and Culus
Atelier Marie, Elie & Anis
Lilie appears in one of the endings of Atelier Marie, Elie & Anis: Message on the Gentle Breeze, where she appears in the academy of the Southern Country. She was the one who introduced a young Anis to alchemy.
Lilie is now the principal of the Southern Academy, which she founded after leaving Salburg (as shown in one of the endings of Atelier Lilie). Her academy is much smaller and laid-back than the strict Salburg one, and due to the lack of staff she also teaches classes despite being the principal. Her portrait still hangs in the Salburg Academy library. In the To the Southern Lands ending she'll call Marie and Elie to the south, impressed by the books they wrote together with Anis.
- Atelier Lilie Ending List Official Website