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The Runestone is a synthesized item in Atelier Rorona: The Alchemist of Arland, Atelier Totori: The Adventurer of Arland and Atelier Meruru: The Apprentice of Arland.

Atelier Rorona[]

"A charm with ancient letters. It will protect you from any misfortune. If you're able to decode the markings, you'll get better effects."
Atelier Rorona description

The recipe book with the recipe for the Runestone can be purchased from Hagel at the Beefy Weapon Shop starting from Assignment 5. It is an accessory that can be equipped to a party member in battle. When equipped, it decreases the chances of getting hit with a status effect, and can also decrease the damage you receive when an enemy attacks. 

Esty may request this from the castle as a possible Front Quest.

Atelier Totori[]

"A talisman said to protect the wearer from various disasters. All alchemists must be able to decode the runes displayed inside of it."
Atelier Totori description

Atelier Meruru[]

"A talisman with runic engravings. Said to protect the wearer from all kinds of calamities. Each of the runes has a different meaning."
Atelier Meruru description

It is used in making the Sealing Amulet.

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Healing Items
Auto AlarmBlack TeaBlank StewCabbage SoupDanishElixirGod's SupperHappy CookieHealing BellHealing SalveMeister TarteMont BlancNectarPassionate SoupSpecial Meat
Battle Items
Absorb GourdAlchemy CandyBag BombBalbombBarrelBeast StatueBlitz SymbolBombBomb IceCannonCraft (Plus Version) • Dark PieDragon PieGlobeLightning BombMeteorMystery AnkhTera BombWitch Salve
Compound Items
ClothDry MetalGoldGolteisenHalmoliumIngotLoclothMuffcotNylonfeatherPlatinePolywoolScale ClothSilkisSilvatiteSter MetalTanbeashTincVelvetis
Synthesized Items
Air DropAlchemy CoalAlchemy YeastArland CrystalBlessed CoinBroken ItemClear GelatinDark WaterGraceful CrystalHappy BasketHealing AromaHelmetHoneyKometOne PowderPolish PowderPure OilPurifierRuby PrismSecret BagShellper HornSpirit's BreathSpring CupSupplementTonicWild ScentWindriderZettel
Equipment
Angel CharmBandit BandanaBunny TailGnardi RingMercurius EyeRunestoneSpirit NecklaceVictory Charm
Key Items
Fantastic WigFriends NecklaceHandmade InstrumentMystery PotionPretty StoneRaptorstein
Pies
Berry PieCabbage PieCream PieDark PieDragon PieDunkelpietHoney PieGolden PieIce PieLiving PieMeat PieMushroom PiePielixirPiemeteorPlain PieRuby PieSeafood PieTea Pie
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Healing Items
Auto AlarmBlack TeaCentury BiscuitChim PieCream PieDanishDrachen ElixirElixirFish CanFish PieHealing SalveHealing SporeHomemade PieHoney PieIksel CourseIksel PlateMeat PieMedical CreamMeister TarteMigraine SyrupMind WaterMont BlancMystery AnkhNectarPassionate SoupPlain PieSecret RemedySpecial MeatTotori BrunchVeggie PieVitality Pill
Attack Items
Armillary SphereBombBomb IceBomber IceCannonCraftConch HornDimension EggDiocraftFishcraftGlobeGlobe SphereHimmelsternLightning BombLightning QuartzMega BombMegacraftMeteorN/ASpirit StoneWitch Salve
Compound Items
ClothDry MetalGoldsteinHalmoliumIngotMuffcotNylonfeatherPlatinePolywoolScale ClothSilkisSilvatiteSter MetalTanbeashTincVelvetis
Synthesized Items
Alchemy CoalAlchemy YeastAnchobeerArland CrystalBeerBomb BoozeBlessed WineButterfliquorCrimson DyeCrystal BallDark WaterDried FlowerDried MeatEther InkFertile PotFish SauceFlourFloral Sour MixGlass BeadsGrape WaterGuardian LiquorHayHoneyLiquorLiving RopeMagic ChainMagic PaintMedicine BaseMillion NightsOne PowderPolish PowderPure OilPure PoisonRainbow OilSaltSpring CupSupplementSweet GemTar LiquidTuna WineZettel
Key Items
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Adventuring goods
Blessed CoinFlying CarpetHappy BasketHeavenly ParasolSecret BagTonicTraveler ShoesWarp Gate
Equipment
Angel CharmCamo CloakFate TalismanGibate AnkhGnardi RingMercurius EyeMythical RingRunestoneShadow BandSpeed GlovesSpirit NecklaceTalismanWarrior Mask
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Healing Items
Auto AlarmCream PieDanishDessert BasketDrachen ElixirDragon BBQElixirGuardian JewelHealing BellHealing SalveHomemade PieJiggly PuddingMeister TarteMerulixirMigraine SyrupMind WaterMont BlancMushroom PieMushroom StewMystery AnkhNectarNew Land RationsPurity VaseRescue SignalSecret TabletSecret RemedySpecial Meat
Attack Items
BombBomb IceCraftDark WaterFortune DiceGlobeLightning BombMagic SwordMeteorMonster PotPeacemakerPinwheelPuni BombRoyal AromaSaluteSpirit StoneWitch Salve
Compound Items
ClothDry MetalHalmoliumIngotMedical LinenMuffcotNylonfeatherPlatinePolywoolRegentiumScale ClothSilkisSter MetalSunliteTanbeashTincWing Quilt
Synthesized Items
Alchemy CoalAlchemy YeastBeerCrimson DyeCrystal BallDried FlowerDried MeatEnhanced PaintFlourGlass BeadsGold NuggetGrape WaterHayHoneyIce Cascade BombKometLiquid SolventLiquorLiving RopeMedicine BaseMagic PaintPolish PowderPotion of YouthPure OilPure PoisonRainbow OilRime CrystalSaltSamsara GearSmall SunSupplementSweet GemSylph BreathTalisman NetTar LiquidTonicUseful ToolWarp GateWisemanipediaZero-G BagZettel
Development Items
Alchemy LampAlchemy SteelAnimal ResonatorBalloon TentBlessed CoinChaos ConductorChim DollDense WoodDowsing RodFate TalismanFireproof PlateFlying CarpetGoddess StatueHandmade BasketHarvest GloveHerbicideJarred MushroomKingdom FlagLand ClaspLiving CartLiving HoeLiving PickaxeLiving SawLiving ShovelMagic StoneMighty FilterMushroom BedMystical GardenNimbus StonePipePreview CrystalRich SoilSafety BoxSand Bag Sealing AmuletSecret BagSky FlameSpring PumpSuction BagSynthesis PieceTime Flow SeedTraveler ShoesWind ControllerUltimate Steel
Equipment
Angel CharmBunny TailCamo CloakGibate AnkhGnardi RingHeroic MedalMercurius EyeMythical RingPocket WatchPromise BandReverse TorqueRunestoneSpeed BeltSpirit NecklaceThief BandanaWarrior Mask
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